Oxidative stress is the relative excess of reactive oxygen species (ROS) versus endogenous defense mechanisms. Abundant evidence has demonstrated the role of ROS, along with reactive nitrogen species (RNS), in the pathophysiology of cardiovascular disease, including heart failure.
Many biomarkers of oxidative stress have been studied as surrogates of oxidative damage. Recently, markers of impaired nitric oxide signaling have also been identified. Many biomarkers have been associated with prognosis and mortality, and some may even be modified by therapy.
However, the clinical utility is limited by less than optimal standardization techniques and the lack of sufficient large-sized, multimarker prospective trials
"Biomarkers of oxidative stress in heart failure"
Trachtenberg BH, Hare JM
Heart Fail Clin. 2009 Oct ; 5(4): 561-77
Related:
Oxidative Stress Causes Heart Failure with Impaired Mitochondrial
Many biomarkers of oxidative stress have been studied as surrogates of oxidative damage. Recently, markers of impaired nitric oxide signaling have also been identified. Many biomarkers have been associated with prognosis and mortality, and some may even be modified by therapy.
However, the clinical utility is limited by less than optimal standardization techniques and the lack of sufficient large-sized, multimarker prospective trials
"Biomarkers of oxidative stress in heart failure"
Trachtenberg BH, Hare JM
Heart Fail Clin. 2009 Oct ; 5(4): 561-77
Related:
Oxidative Stress Causes Heart Failure with Impaired Mitochondrial
Although previous studies suggested that oxidative stress plays a pathological role in the development of heart failure, no direct evidence has been documented so far. In order to investigate the pathological significance of oxidativeOxidative stress and redox signalling in cardiac hypertrophy
substantial evidence suggests the involvement of oxidative stress in the pathophysiology of congestive heart failure and its antecedent conditions such as cardiac hypertrophy and adverse remodelling after mi. oxidative stress describesObesity seen protective in cases of heart failure (Reuters)
Adequate antioxidants and foods that help manage oxidative stress and support the immune system may benefit athletes during and after exercise. In addition to the unique amino acid profile of whey buy bulk dmae bitartrate it also ...Vitamins, Minerals and Chronic Heart Failure
Vitamins B6, B12 and folate all tend to reduce levels of homocysteine, which is associated with increased oxidative stress. Carnitine, co-enzyme Q10 and creatine supplementation have resulted in improved exercise capacity in patients ...
